Plasma exchange in the treatment of chronic severe hepatitis B.doc

 PAGE \* MERGEFORMAT 11 Plasma exchange in the treatment of chronic severe hepatitis B [Abstract] Objective To observe plasma exchange (PE treatment of chronic severe hepatitis B patients. Methods Infectious Diseases Hospital in Tianjin Tanggu 31 hospitalized patients with chronic severe hepatitis B, are based on the combined therapy in the medical treatment of combined PE. Observed before, clinical symptoms and biochemical changes in mortality and adverse reactions. The results, compared with PE treatment, symptoms improved significantly after treatment, TB, ALT, PTA, NH3 decreased significantly (P lt;0.01, Ca decreased (P lt;0.05, renal function (BUN, Cr, electrolytes (K, Na, ALB, no significant change in the total mortality rate was .31 cases were 45.16%, no severe adverse reactions. Conclusion PE is a safe and effective treatment for chronic severe B hepatitis with positive and reliable auxiliary support and treatment, based on the joint medical treatment can improve liver function in patients with severe viral hepatitis and coagulation status, maintain homeostasis, and can improve survival, reduce mortality, is a species worthy of further study of new methods. [Keywords:] plasma exchange with chronic severe hepatitis B Abstract: Objective To study the efficacy of plasma exchange (PEin the treatment of chronic severe hepatitis B. Methods Thirty-one of those suffering from chronic severe hepatitis B received plasma exchange combined with comprehensive treatment. Results The serum bilirubin, ALT, PTA, NH3 , Ca were decreased (P lt;0.01, P lt;0.05) compared with that before treatment. Total death rate was 45.16%. There appeared no severe adverse reactions. Conclusion PE is one kind of safe and effective artificial supporting regime. Combined with other basic therapy of PE is valuable to improving serious toxic hepatitis patient’s liver function and enhancing the survival rate, which is the very subject deserving further study and efforts. Keywords: