Plasma TuM2-PK detection in lung cancer patients value.doc

 PAGE \* MERGEFORMAT 3 Plasma TuM2-PK detection in lung cancer patients value Author: Yue Han Dynasty Bo Chen Zhijun Ye ZHANG Yong-kui [Keywords:] TuM2-PK in plasma of lung cancer Lung cancer is a serious malignancy affecting human health, one of its incidence and mortality in the world account for neoplastic diseases in the first. TuM2-PK is a recent study found that a new tumor marker [1], this study from April 2005 to September 2007 by detecting TuM2-PK in lung cancer, benign lung disease patients and healthy plasma concentrations changes, to evaluate the plasma TuM2-PK in lung cancer clinical significance. A clinical data 1.1 General Information 67 cases of lung cancer patients, were characterized by histology or cytology confirmed 43 cases of male and female 24 cases; average age (56.7 ± 11.9) years of age. In which 51 patients with non-small cell lung cancer (adenocarcinoma 32 cases, squamous cell carcinoma 19 cases), small cell lung cancer in 16 patients. Cancer Society published the adoption of international TNM classification for staging: Ⅰ and Ⅱ in 22 cases, Ⅲ a period of 21 cases, Ⅲ b phase and Ⅳ 24 cases. Group of 31 patients with benign lung disease, male 22 cases, 9 female, mean age (49.3 ± 15.7) years of age. 17 cases in which Bullae, 6 cases of chronic bronchitis, bronchiectasis in 5 cases, tuberculosis in 3 patients. Over the same period 32 cases of physical examination as a healthy control group, 15 males and 17 females; average age (45.7 ± 12.1) years of age. 1.2 Methods Take subjects fasting blood 2ml, EDTA-K2 anticoagulant, centrifuged samples, -30 ℃ cryopreservation for inspection using sandwich ELISA, plasma TuM2-PK levels. Kit using the German ScheBo.Tech company. According to Kit, as shown in order to 15U/ml threshold, ≥ 15U/ml positive, amp;lt;15U/ml negative. 1.3 Statistical analysis Specimens were used to compare the number of t test, χ 2 test was used to compare rates. 2 Results 2.1 in patients with lung canc