Polysaccharide molecular weight and structure of research.doc

 PAGE \* MERGEFORMAT 18 Polysaccharide molecular weight and structure of research [Abstract] pharmacological effects of the current polysaccharide relatively active, and its molecular weight and molecular weight distribution and chemical structure determination of further in-depth study of polysaccharide-specific and structure-activity relationships and mechanism-based efficacy. The article summarizes the molecular weight and molecular weight distribution of polysaccharide and the chemical structure and research methods. [Keywords:] polysaccharide; molecular weight; molecular weight distribution; chemical structure; biological activity Abstract: The study on pharmacological action of polysaccharide of traditional Chinese drug is more active at present, but the definition of molecular weight and molecular weight distribution and chemical constitution has become the foundation of better study on specificity and structure-function relationship and drug action mechanism of polysaccharide. The methods of study on molecular weight and molecular weight distribution and chemical constitutuion of polysaccharide were reviewed in this paper. Keywords:: Polysaccharide of traditional Chinese drug; Molecular weight; Molecular weight distribution; Chemical constitution; Biological activity Polysaccharide is usually caused by hundreds or even thousands of monosaccharide composition of the polymer homopolymer or copolymer, which can be hydrolyzed to more than simple sugars. Polysaccharide found in plants and animals among the higher plants and algae, they are inside the cell wall or cell components; in bacteria and fungi, they may both cellular components, but also a product of metabolism. Large molecular weight polysaccharides, their nature substantially different from simple sugars and oligosaccharides. Modern research found that Poria, Astragalus, Polyporus umbellatus, medlar, Bupleurum root, ginseng, mushrooms, Coriolus versicolor, white fungus, Ganoderma lucidum, Co