Positron emission tomography in lung cancer diagnosis and treatment progress.doc

 PAGE \* MERGEFORMAT 13 Positron emission tomography in lung cancer diagnosis and treatment progress [Abstract] At present, China has increased the incidence of lung cancer incidence rates for malignant tumors first. Early diagnosis of lung cancer to become the key to a cure. Routine chest X ray, CT, bronchoscopy, cytology, serology and so there are limitations. In recent years, positron emission tomography (PET) in clinical application of a gradual increase, it can accurately reflect the sensitivity and lung cancer cells, abnormal metabolism, protein synthesis, DNA replication and cell proliferation, especially in the diagnosis of solitary pulmonary nodules. PET not only improve the accuracy of the diagnosis and staging of lung cancer, but also for lung cancer radiotherapy and chemotherapy program in the formulation and efficacy assess significance. In this paper, PET in lung cancer and mediastinal lymph node staging in lung cancer radiotherapy and chemotherapy as well as its application, etc. are reviewed. [Keywords:] lung cancer; PET; Diagnosis Primary lung cancer is mainly of primary bronchial cancer, cancer mortality, ranking first among Chinese cities, even if the early stage non-small cell lung cancer chemotherapy after surgery, the 5-year survival rate is only about 40% [1]. How early diagnosis of lung cancer staging, early detection of recurrence and metastasis, and rational treatment of radiotherapy and chemotherapy, as well as monitoring the efficacy of raising the survival rate of patients with lung cancer is very important. Clinical examination of the current methods used are mainly CT, bronchoscopy, cytology, serology, etc., but there are limitations, such as the qualitative diagnosis of solitary pulmonary nodules, CT sensitivity of 12% ~ 63% [2 ]; bronchoscopic biopsy and brush inspection sensitivity for lung cancer is only 70% ~ 80% [3]; CT guided lung biopsy diagnostic accuracy rate was 97%, but there are pneumothorax, bleeding and other com