Postconditioning with acute myocardial infarction intervention of.docVIP

 PAGE \* MERGEFORMAT 15 Postconditioning with acute myocardial infarction intervention of [Abstract] Objective postconditioning with acute myocardial infarction (AMI) in patients with myocardial infarction after emergency intervention area, myocardial perfusion and cardiac function in. Methods of emergency within 12 h of percutaneous coronary intervention (PCI), 122 cases of acute myocardial infarction were randomly divided into control group (n = 87) and (ischemic) postconditioning group (n = 35). the patients who underwent emergency PCI treatment. the control group after recanalization of infarct-related interventions are not applied; postconditioning infarct related artery reperfusion within 1 min after application of low pressure filling and retracement of the balloon repeated 3 times, each process of the 30 s, after measured blood creatine kinase (CK), creatine phosphate kinase isoenzyme (CK MB), Fas / FasL, ST fall rate correction TIMI frame count (CTFC). after 6 months of single-photon emission computed tomography (SPECT) examination. the results meet the group CK, CK MB peak was significantly lower than the control group ((1 179 + -992) U / L vs (1 643 + -1 021) U / L; (120 + -76) U / L vs (160 + -88) U / L; P lt;0.05)); peak after adaptation was significantly lower than the control group FasL ((3 587.8 + -231.5) pg / ml vs (4 412.4 + -105.7) pg / ml, P lt;0.05)); sFas level of intervention 24 h began to decrease significantly compared with the control group (P lt;0.05), and lasted until 7 d (P lt;0.05). CTFC after adaptation was significantly faster than the control group (26.7 + -11.2 vs 31.4 + -9.5, P lt;0.05), surgery ST after the fallgt; 50% was significantly higher (74.3% vs 54.0%). After 6 months of SPECT examination, after the adaptation was resting redistribution index decreased ((10.8 + -9.6)% vs ( 18.5 + -12.8)%, P lt;0.05). Conclusion postconditioning reduce myocardial injury in AMI patients, apoptosis and improve myocardial perfusion and