Preparation and delivery of ibuprofen analysis of the nature.docVIP

 PAGE \* MERGEFORMAT 10 Preparation and delivery of ibuprofen analysis of the nature Of: Nie Chuanping Caohong Zhao Guowei Ying [Abstract] orthogonal design to pass the body ibuprofen prescription ibuprofen prepared to pass the body size distribution (122.3 + -31.9) nm, and water-methanol (20:80,0.1% TFA) as the mobile phase, HPLC measured the average encapsulation efficiency was 48.92%. the initial stability study showed that at low temperature (4 ℃) storage of 7 d, the average particle size and distribution of products, small changes, drug leakage less than 3%, with the more stabl