Primary breast diffuse large B cell lymphoma in 1 case.docVIP

 PAGE \* MERGEFORMAT 6 Primary breast diffuse large B cell lymphoma in 1 case [Keywords:] breast cancer; lymphoma, large cell, diffuse; primary Patients, female, 31 years old, was found breast lumps 1 month hospitalization. Patients in December 2009 a unwittingly palpable right breast lump, about the size of pigeon eggs, occasional breast pain, no fever, no weight loss, no nipple haemorrhagic. line of private hospitals in Spain tumor puncture cytology, considered as benign lesions. mass without progressive increase. for the sake of further treatment to our clinic in order to “right breast mass” admitted to our department. examination: vital signs were stable, clear mind, no yellow skin and sclera stained, superficial and supraclavicular lymph nodes are not touched, lungs clear breath sounds, heart rate, Qi, and abnormal heart sounds and did not hear noise, abdomen soft, liver, spleen not palpable, the whole no abdominal tenderness, bowel sounds 3 to 4 times / min. breasts symmetrical shape, the nipple with no sink, no haemorrhagic discharge, skin inflammation and skin ulcers, no dimple sign and orange peel-like change; right breast outside upper quadrant palpable size of 3.5 cm 3.0 cm mass within the inferior quadrant palpable right breast and about 1.5 cm 1.0 cm sized mass, ill-defined, quality, the smooth, no tenderness, activity may be; no time left internal mammary tumors. admission after January 27, 2010 under general anesthesia the right modified radical mastectomy surgery, pathology routine: (right breast) malignant lymphoma, diffuse large B cell type. immunohistochemical staining: ER (-); PR ( -); CerbB-2 (-); LCA (+); CK-wide (-); E-cad (-); S-100 (-); CD79(+); CD20 (+); CD3 (a small amount of +); CD45RO (small +); Ki-67 (+ about 90%); CD10 (+); BCL-6 (+); Mum-1 (+). lactate dehydrogenase 205 U / L, normal blood , negative for hepatitis B immune indicators suggest, 2-microglobulin 1.3 mg / L, uric acid 305mol / L, heart-Tip in the normal range,