Principles of drug treatment Gastrinoma.doc

 PAGE \* MERGEFORMAT 6 Principles of drug treatment Gastrinoma [Abstract] Objective To study the principles of drug treatment gastrinoma, analysis of drugs in different stages of treatment options and the application of principles. Method in our department from 2006 to 2009 for treatment of gastrinoma information on drug efficacy in patients with follow-up survey . Conclusion Depending upon the patients treated with different drugs and medical treatment dosage. [Keywords:] the principles of drug treatment gastrinoma Gastrinoma (gastrinoma) is a function of the tumor with the secretion of gastrin and its clinical manifestations of gastric juice, gastric acid hypersecretion, hypergastrinemia, multiple, atypical location of refractory peptic ulcer, diarrhea syndrome group. above the Zollinger and Ellison syndrome group was first reported in 1955, this levy can be gastrin secretion of tumor (gastrinoma) or antral G cell hyperplasia. caused by the former is called the Zollinger-Ellison syndrome type , which is caused by the latter as I type. about 20% of patients with gastrinoma can be expressed as multiple endocrine neoplasia type I syndrome (multiple endocrine neoplasia type-I, MEN-I), also known as multiple endocrine neoplasia type I. peptic ulcer, caused by the disease were less than 1%. can occur at any age (7 to 90 years old), but the more common 35 to 65 years old . men slightly more than women. gastrin, although the majority of malignant tumors, but the tumor is small, slow development, so the tumor itself is rarely cause noticeable symptoms, to the late phase of disease, invasive cancer symptoms appear side. its clinical performance was mainly concerned with the large number of gastric acid secretion. Once gastrinoma resection, the disease is cured. malignant gastrinoma of its relatively low degree of malignancy, slow growth, although with larger tumors or transferred elsewhere, were still normal Life for many years. It is reported that 5 to 10