Produced exfoliative tongue fur in children with asthma the immune mechanism.doc

 PAGE \* MERGEFORMAT 3 Produced exfoliative tongue fur in children with asthma the immune mechanism Authors: Lifu Feng, Li Guo-Gang, WU Zhong, Li Jing, Zhang Xiao-Ying, Wang Huifang, Wang Yi-Qin [Keywords:] of exfoliative tongue fur; [Abstract] Objective: From the immunological point of view of the formation of exfoliative tongue fur in children with asthma mechanism. Methods: Immunohistochemical Detection of exfoliated epithelial cells of tongue coating keratin 13 and bcl2 protein content. Application of flow cytometry in peripheral blood CD4 and cellular chemokine receptor 3 (cell chemokine receptor3, CCR3) expression levels. Radioimmunoassay of serum cortisol levels. Results: The group of exfoliative tongue fur in children with asthma, peripheral blood CD4 and CCR3 levels were significantly higher than that of non-exfoliative tongue fur in asthmatic group and normal group (P amp;lt;0.05); asthma exfoliative tongue fur in groups, non-asthmatic group of exfoliative tongue fur in serum cortisol levels lower than the other groups (P amp;lt;0.05). Exfoliative tongue fur in asthma and non-exfoliative tongue fur in serum IgE levels were significantly higher than other groups (P amp;lt;0.05). Exfoliative tongue fur in asthma group, non-asthmatic group of exfoliative tongue fur in exfoliated epithelial cells of tongue coating keratin 13 were significantly lower than that of non-exfoliative tongue fur in asthma group, non-exfoliative tongue fur in non-asthmatic group and the normal control group (P amp;lt;0.05). Groups of exfoliative tongue fur in children with asthma Tongue exfoliated epithelial cells bcl2 protein content and the remaining groups showed no statistical difference. Conclusion: The formation of exfoliative tongue fur and the immune response is closely related to a lower level of serum cortisol, CD4, and CCR3 increased, may have contributed to the formation of exfoliative tongue fur. Meanwhile, the tongue epithelium keratinized barriers and tongue e