Prolonged pregnancy trophoblast cell expression of Survivin.doc

Prolonged pregnancy trophoblast cell expression of Survivin Of: Chen Cairong, Wang self, GUO Xiao-yan, Liu Kunping, Hu Qinglan [Abstract] Objective To observe the prolonged pregnancy in patients with inhibitor of apoptosis protein Survivin expression in trophoblast cell layer, of trophoblast cell apoptosis and the relationship between prolonged pregnancy. Methods Immunohistochemical method (SP method in 10 cases and 10 cases of prolonged pregnancy normal term pregnancy placenta maternal cell layer of Survivin expression were detected and compared. Results Results Survivin expression in trophoblast cell layer of prolonged pregnancy group was 6.67 + -0.45, term pregnancy group was 8.83 + -0.67, Survivin expression in the two groups There were significant differences (P lt;0.05). Conclusion trophoblast cell layer and decreased expression of inhibitor of apoptosis protein Survivin, which may be related to prolonged pregnancy. [Keywords:] expired gestational trophoblastic placental apoptosis protein Survivin [Abstract] Objective To study the relationship between postdate labor and the trophoblast apoptosis by observing the expression of Survivin protein in the trophoblasts of placenta.Methods Immunnohistochemistry was used to detect the expression of Survivin protein in the trophoblasts of placenta which were taken from 10 samples of postdate labor and 10 samples of full term labor.Results The expressionin of Survivin protein in the trophoblasts of postdate labor was (PU: 6.67 + -0.45) and in full term labor group was (PU: 8.83 + -0.67). The expression of Survivin protein in the trophoblasts of full term labor was remarkably higher than that in the placenta of postdate labor. There was significant difference between them.Conclusion Survivin may be inhibited by trophoblast apoptosis. it might be correlated with the postdate labor. [Keywords:] placenta, postdate labor, trophoblasts, apoptosis, Survivin In recent years, with the proposal of apoptosis, molec