Proton magnetic resonance spectroscopy imaging in temporal lobe epilepsy of.docVIP

Proton magnetic resonance spectroscopy imaging in temporal lobe epilepsy of [Abstract] magnetic resonance spectroscopy is currently the only noninvasive molecular level in the quantitative analysis of metabolites of the detection method, can do many brain diseases, early diagnosis and treatment monitoring. This paper mainly in proton magnetic resonance spectroscopy temporal lobe epilepsy diagnosis and treatment of the application were reviewed. [Keywords:] magnetic resonance spectroscopy; temporal lobe epilepsy Temporal lobe epilepsy (temporal lobe epilepsy, TLE) can be classified according to origin of attacks for the issuance of the hippocampus and amygdala lateral temporal lobe seizures, the majority of these patients show hippocampal sclerosis exist, but the performance of bilateral hippocampal sclerosis who showed more asymmetry . TLE have the common characteristics of epilepsy, the abnormal discharge repeatedly by high frequency synaptic connections and posttetanic facilitation role can be induced by the surrounding and distant synchronization of neuronal discharges, which led to the continuous spread of potential anomalies, which is not limited to a region, and will spread to the ipsilateral hemisphere and contralateral hemisphere. and most surveys have shown that temporal lobe epilepsy often intractable, the choice of drug types and dosages more difficult, so that the surgical treatment of patients increased . because of magnetic resonance spectroscopy imaging (magnetic resonance spectrosco-py, MRS) by the determination of brain metabolism in the temporal lobe epileptic foci based on the nature of preoperative localization studies and surgery to predict postoperative outcome and antiepileptic epileptic drug efficacy testing on the application of great value, are summarized below. 1 MRS and study the basic principles of temporal lobe epilepsy advantage MRS was used in 1990 and clinical epilepsy. Matthews [1] first reported epileptic patients