Qin-Ba Mountain Aristolochiaceae two kinds of commonly used herbs in the aristolochic acid content analysis.docVIP

 PAGE \* MERGEFORMAT 13 Qin-Ba Mountain Aristolochiaceae two kinds of commonly used herbs in the aristolochic acid content analysis [Abstract] Objective To analyze the determination of production Asarum Qinba Mountain Aristolochia sieboldii Miq. And Hanzhong fangchi A. heterophylla Hemsl. Two kinds of medicinal herbs in the content of aristolochic acid A. Methods Column: Agilent ODS (5 μ m, 4.6 mm * 250 mm); mobile phase: methanol - acetonitrile -1% glacial acetic acid (47:17:36); flow rate of 1.0 ml / min; column temperature: room temperature; detection wavelength 315 nm. Results Asarum of aristolochic acid A, the average content of 74.1 μ g / g, Hanzhong fangchi aristolochic acid A in the average content of 2.14 mg / g. Conclusion of Hanzhong Tetrandrae of aristolochic acid A in aristolochic acid content of Herba Asari A content of about 30 times. [Keywords:] Asarum Hanzhong fangchi aristolochic acid A high-performance liquid chromatography Aristolochiaceae Asarum plants for the North Asarum Asarum heterotropoides Fr.Schmidt var. Mandshuricum (Maxim.) Kitag., Chinese Asarum A.sieboldii Miq.’s Dry the whole plant, mainly distributed in Liaoning, Jilin, Heilongjiang, Shaanxi, Shandong provinces. Clinic for expelling wind and cold-dispelling, Tongqiao pain, temperature and lungs of drinking [1]. Hanzhong Tetrandrae different for Aristolochiaceae Aristolochia delavayi Aristolochia heterophylla Hemsl.’s Dried roots, was born in the hillside shrubs, the main producer in Shaanxi. Of the original winding vine plants, high-2 ~ 3 m, the root cylindrical, long 8 ~ 15 cm, diameter of 2 ~ 5 cm, with fragrance, skin yellow-brown or grayish brown. Cold, bitter, can Qufeng, dampness, analgesic, used for edema, urine negative, rheumatism Bitong embolism. In recent years, Aristolochiaceae Plants contain aristolochic acid, kidney damage caused by the clinical reports and Toxicology widespread attention, many studies have reported a number of commonly used herbs containing