Quantitative propofol drugs on human EEG power spectrum percentage of.docVIP

 PAGE \* MERGEFORMAT 11 Quantitative propofol drugs on human EEG power spectrum percentage of Of: Liu Ling Ling, Wang Liwei Eddie Ng, Ti-Jun Dai [Abstract] Objective To observe the quantitative propofol drugs on human EEG (QPEEG) band power percentage. Methods 20 young volunteers, each group of 10 people, evenly divided between men and women, respectively, intravenous propofol 1.0 mg / kg, 1.5 mg / kg, observe and compare the 2 groups before and after administration of the band power percentage QPEEG. Results After propofol injection, the percentage of group 2 QPEEG band power were increased (P lt;0.01)), 2 ~ 5 min and reached peak about 10 min recovery .1.5 mg / kg group QPEEG band power increase was larger than the percentage of 1.0 mg / kg group (P lt;0.05, P lt;0.01). Conclusion Propofol dose-dependently increased the percentage of people QPEEG band power, suggesting QPEEG percentage band power may be the depth of propofol anesthesia monitoring indicators. [Keywords:] propofol; quantitative EEG drugs; depth of anesthesia; monitoring; band; power percentage Abstract: Objective To investigate the effects of propofol on the percentage of band power of quantitative pharmaco-EEG (QPEEG). Methods 20 healthy adults were randomly divided into 2 groups (P1.0 amp; P1.5, n = 10 each) and were given iv injections of 1.0 mg kg-1 or 1.5 mg kg-1 of prpofol, respectively. The EEG samples were obtained before and at regular intervals following the propofol injections. Power spectral analysis was conducted to check the EEG variations before and after the propofol iv injections. Results The percentage of band power of QPEEG significantly increased in both groups (P lt;0.01), reached its peak at 2-5 min, and then returned to normal at 10 min. The increase of the percentage of band power of QPEEG in group P1.0 was greater than that in group P1.5 (P lt;0.05, P lt;0.01). Conclusion Propofol increased the percentage of QPEEG power at band in a dose-dependence