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Rabeprazole triple therapy for treatment of Peptic Ulcer
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Rabeprazole triple therapy for treatment of Peptic Ulcer
[Keywords:] peptic ulcer, effect
We applied since March 2006 rabeprazole triple therapy of 60 cases of peptic ulcer, and achieved good results, are summarized below.
1 Materials and Methods
1.1 General Information
Out-patient endoscopy proved to be benign peptic ulcer, rapid urease test HP (+ 180 patients were randomly divided into treatment group and observation group and the observation A B groups of 60 patients, 41 cases were male , 19 females .180 patients aged 16 to 69 years, average age 43 years old, weighing 36 ~ 83kg. The average weight of 66.5kg. three groups of age, sex, body weight was no significant difference (Pgt; 0.05).
1.2 Methods
Three groups of patients with oral drugs are used. Zhuhai, China Tong treatment group pharmaceutical production rabeprazole enteric-coated pellets 10 mg capsules once every night, clarithromycin 0.5 g once daily, amoxicillin 1.0 g twice daily; observed A group with ranitidine 150 mg twice daily, clarithromycin 0.5 g once daily, amoxicillin 1.0 g twice daily; observation of B group was treated with omeprazole 40 mg every Day one, 0.5 g once daily clarithromycin, amoxicillin 1.0 g twice daily, for 4 weeks after the review of endoscopy and rapid urease test HP, asked whether the course of treatment in patients with adverse reactions.
2 Results
Treatment group compared with the observed effect in group A was significantly different (P lt;0.05, treatment group compared with the observed effect in group B no significant difference (Pgt; 0.05, observed A group B group and observed effect was significant difference compared (P lt;0.05. three groups of patients during the treatment had no obvious adverse reactions. Table 1. Table 1 Efficacy of three treatment methods table (a little note: the treatment group rabeprazole group observed A group Rainey for the D group, B group and omeprazole group observed
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