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Received by e-mail rather children cough syrup antitussive and expectorant in rats
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Received by e-mail rather children cough syrup antitussive and expectorant in rats
Author: Chen Ling, Ren Yuan, Ma, Zhi-Wang Wang, Wu Cathay Abstract: Objective: To study children antitussive and expectorant cough syrup ning role. Methods: Antitussive experiment with ammonia and sulfur dioxide-induced cough, phlegm out the use of tracheal phenol red secretion in mice and rat tracheal mucus secretion France France. Results: The children cough syrup Ning ammonia and sulfur dioxide can inhibit the cough response induced in mice, the mice and rat tracheal mucus secretion of a clear facilitating role. Conclusion: The children cough syrup rather obvious cough, phlegm role.
Keywords:: children cough syrup Ning; antitussive; expectorant; experimental study
Children cough syrup is a clinical experience rather party made syrup preparation, clinical respiratory tract infections in children caused by cough, sputum difficult to discharge a good effect. This study was carried out animal experiments were observed for their clinical studies, will now report the results as follows.
An experimental material
1.1 Drugs and reagents
Ning children cough syrup, home-made; CHUANBEIPIBA syrup, the national medicine accurate No. 4 Pharmaceutical Co., Ltd. Chuan Purui production, batch number: 20,030,121; phenol red, Tianjin days the new Fine Chemical Plant Development Center, batch number: 970,802; ammonia, Xi’an Chemical Reagent Factory production, batch number 980,511; anhydrous sodium sulfate, Xi’an Chemical Reagent Factory production, batch number 980,811; sulfuric acid, Xi’an Chemical Reagent Factory production, batch number 981,112.
1.2 Animals
Kunming mice, weighing 18 ~ 25 g, Qualified Certificate No.: No. 14-005 Medical dynamic character, provided by the Lanzhou Medical College; Wistar rats weighing 180 ~ 200 g, Qualified Certificate No.: No. 14-006 Medical dynamic character , provided by the Lanzhou Medical College.
2 Methods and Resul
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