Recombinant human epidermal growth factor treatment of children with 48 cases of epistaxis.docVIP

 PAGE \* MERGEFORMAT 4 Recombinant human epidermal growth factor treatment of children with 48 cases of epistaxis [Keywords:] recombinant human epidermal growth factor epistaxis children Nasal bleeding is a common ENT children is nasal and sinus disease, or some common symptoms of systemic disease is one factor to the nasal cavity are mostly of children, more performance for the septal area Klinefelter bleeding, can be unilateral, but also repeated bleeding may be bilateral. We June 2007 to August 2009 to 48 outpatient children with children with nasal bleeding with recombinant human epidermal growth factor (epidermal growth factor, EGF) treatment, receipt of satisfactory results, reported as follows. 1 Materials and Methods 1.1 Clinical data 95 cases of children with epistaxis were randomly divided into two groups, observation group, 48 patients aged 3 to 14 years, mean 6 years old, duration of 1 to 6 years; 47 patients in control group, aged 4 to 14 years, mean age 7 years, duration 1 to 6 years. Both groups were routine blood investigations, prothrombin time and activated partial thromboplastin time were within the normal range. observed group, 16 patients had nasal mucous membrane dryness, congestion, septal, and Clinton on one side erosion area, bleeding, the rest are bilateral erosion, recurrent bleeding, of which 3 cases of inferior turbinate front-end erosion, hemorrhage; the control group, 17 patients with nasal mucosa dryness, congestion, septal side g’s area erosion, bleeding, other bilateral erosion, repeated bleeding, two had the front end of inferior turbinate erosion bleeding. 1.2 Treatment First observation of bilateral nasal cavity, specifically bleeding site, with 1% ephedrine and sticky cotton sheet sticking scab and blood clot, and then observe the group in front with a shake of the EGF solution nasal septum 2 g’s area with spray spray spray two times per day, 10 d to 1 course of treatment; the control group in front wit