Refractory Peptic Ulcer Cause Analysis and Countermeasures.doc

 PAGE \* MERGEFORMAT 9 Refractory Peptic Ulcer Cause Analysis and Countermeasures [Abstract] all the treatment of peptic ulcer, but the cure rate is not high. In this paper, the reasons for its refractory analysis, and made a personal opinion, summed up a number of measures had proved effective in clinical practice to obtain a more satisfactory results. [Keywords:] Refractory; peptic ulcer; causes; countermeasures Peptic ulcer or gastric ulcer (GU) and duodenal ulcer (DU), is a common disease of mankind, showing a worldwide distribution, about 10% of the population suffered from the disease in life. 20th century, the gradual increase in the incidence of the disease in developed countries higher than the northern South China, urban than rural. The past 20 years, DU incidence on the rise. As a common disease, why is there a series of difficulties in treatment? I have more than ten years, this disease refractory to a number of studies are reported as follows. A cause of refractory peptic ulcer 1.1 Eradication of Helicobacter pylori (Hp) is not completely 1.1.1 eradication of Hp medication non-standard although everyone knows that eradication of Hp in the treatment of peptic ulcer of the importance, but in the whole course of treatment will truly uphold the eradication of Hp in patients with triple therapy are not many adhere to quadruple therapy very few such patients is, which is part of the medical staff there is a lack of expertise in addition to digestion, but also with patients suspected of medications have certain relationship troubles. 1.1.2 Eradication of Hp while ignoring its resistance considerations [1] According to the data indicate that, Hp has produced a variety of antibiotic resistance, including macrolide drugs, clarithromycin resistance rate of 10 % ~ 20%, nitroimidazoles metronidazole in the highest, 10% ~ 70%, β -lactam in the amoxicillin resistance emerging, Brazil reported that its 29%, quinolones to ring Nesa stars as the r