Research on the pathogenesis of acute pancreatitis in Progress.docVIP

 PAGE \* MERGEFORMAT 14 Research on the pathogenesis of acute pancreatitis in Progress [Abstract] acute pancreatitis (acute pancreatitis, AP) basic and clinical research has been a hot and difficult, its pathogenesis has not yet been fully clarified. With the continuous deepening of the study, in addition to the traditional ‘trypsin self-digestion’ theory, the excessive activation of white blood cells - inflammatory factors cascading waterfall effect, pancreatic microcirculatory disturbances, apoptosis theory, theory of intestinal bacterial translocation, pancreatic gland calcium overload bubble theory, theory and many other rich people’s understanding of the pathogenesis of AP. Special studies on the pathogenesis of AP to do a review of progress. [Keywords:] progress in the pathogenesis of acute pancreatitis Acute pancreatitis (acute pancreatitis, AP) is to advance the pancreatic duct or acinar trypsin activation within the pancreatic tissue itself after the cause of acute chemical digestion caused by inflammation, which is the study AP pathogenesis of the dominant theory, but In recent years, clinical practice and research shows that, AP in the pathogenesis is a complex, comprehensive pathological physiological processes. Although the pathogenesis of AP has not yet been fully clarified, but the joint efforts of experts at home and abroad in recent years, the study progressed very quickly and put forward many new doctrines to the awareness of the progress of the disease and guiding clinical treatment, to reduce the mortality plays an important role. A theory of the pancreas to digest itself 1.1 pancreatic duct obstruction and bile reflux Gallstone incarcerated at the lower end of common bile duct or pancreatic duct caused by bile reflux a common channel, the activation of trypsin caused by pancreatic acinar injury is long since the traditional view, but for some unexplained acute pancreatitis and common bile duct and pancreatic duct openings in the respe