Resistin C-reactive protein and microvascular complications of type 2 diabetes early relationship.docVIP

 PAGE \* MERGEFORMAT 18 Resistin C-reactive protein and microvascular complications of type 2 diabetes early relationship Study: Cheng Shu-ying, Jingai Yu, Yang Chunyan, Ma Jian whole, Yuan Xiaohong, Chen Bo [Abstract] Objective To explore type 2 diabetes mellitus (T2DM) patients with plasma resistin, serum C-reactive protein (CRP) levels and early T2DM relevance of microvascular disease. Methods 60 patients with clinically diagnosed T2DM patients, divided according to whether microvascular complications group for the microvascular complications (DMA group) and group without microvascular complications (NDC group), n = 30. Another year examination of 24 cases selected healthy volunteers as control group (NC group). by double antibody sandwich enzyme-linked immunosorbent Assay 3 Determination of plasma resistin concentration group, scattering Immunoturbidimetry serum CRP levels measured by radioimmunoassay of insulin, glucose oxidase method, serum lipids automatic biochemical analyzer. Results DMA plasma resistin and serum CRP were higher than in NDC group and NC group, the difference was statistically significant (P lt;0.05). Pearson (or Spearman) correlation analysis showed that plasma resistin and fasting insulin (FIns), glycosylated hemoglobin (HbA1c), insulin resistance index (HOMA-IR), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) was positively correlated (r = 0.582,0.433,0.435,0.342,0.485, P all lt;0.05), and fasting plasma glucose (FPG ), triglyceride (TG), body mass index (BMI), high density lipoprotein cholesterol (HDL-C) had no correlation with serum CRP and urinary albumin (UALb), plasma resistin, HOMA-IR, FIns , HbA1c was positively correlated (r = 0.388,0.240,0.283,0.279,0.318, P all lt;0.05), and HDL-C was negatively correlated (r =- 0.235, P lt;0.05). Conclusion Plasma resistin, serum CRP may be microvascular disease and type 2 diabetes occurrence and development is closely related to [Keywords:] resistin, type 2