Resting heart rate and target organ damage in Progress in.doc

 PAGE \* MERGEFORMAT 16 Resting heart rate and target organ damage in Progress in Keywords: resting heart rate; cardiovascular; target organ The past, a number of large clinical studies have suggested that heart rate (HR) in hypertension, acute myocardial infarction, non-ST elevation acute coronary syndrome, chronic heart failure, insulin resistance and abnormal glucose and lipid metabolism in cardiovascular disease prognosis has important significance, is an independent cardiovascular disease risk factors of mortality, HR for the classification and prognosis of cardiac function is important, HR increased by increasing the pressure on the arterial wall may be a direct result of atherosclerosis, in Hypertension plays an important role in kidney damage, and accelerate the development of hypertension 1,2. In many decision factors of myocardial oxygen consumption in the activities, HR is the most important determinant, HR faster not only reduces the myocardial oxygen supply, increased myocardial oxygen consumption, resting HR (RHR) reduced the increase in ventricular filling time , so that the reduced cardiac output and lead to a further increase of coronary insufficiency, myocardial contractility reduction can be induced by heart failure or cardiogenic shock, increased mortality of acute myocardial infarction, which is closely related to HR and cardiovascular disease. Some studies suggest 3, basic HRgt; 84 times / min and 5 to 10 years after the occurrence of myocardial infarction was significantly related to the forecasting ability of elevated levels of cholesterol. 1 Concept At the 20th session of the European Society of Cardiology on, RHR and its target organ damage in hypertension caused wide concern, reiterated the RHR in hypertension and ischemic heart disease in the importance and relevance 4. RHR is the supine resting state HR, RHR more than 90 times is an independent risk factor for coronary heart disease 5. 6 Jamerson made other people ov