Single Chinese medicine and its extracts tubulointerstitial injury prevention Experimental Research.docVIP

 PAGE \* MERGEFORMAT 21 Single Chinese medicine and its extracts tubulointerstitial injury prevention Experimental Research 【Key Words】 Chinese medicine;,,,, glomerular disease;,,,, tubulointerstitial damage;,,,, experimental study Keywords: Chinese medicine; glomerular disease; tubulointerstitial damage; experimental study Glomerular diseases caused by various reasons, often accompanied by tubulointerstitial damage, renal tubular interstitial damage is to determine the 10-year kidney survival rate of the most important factor, its impact is important than glomerular lesions [1]. Therefore, glomerular disease, tubulointerstitial injury research, has drawn increasing attention of scholars home and abroad. However, modern medicine for the disease caused by glomerular tubulointerstitial injury prevention and control there is no reliable therapy, many studies still at an experimental stage. In contrast, Chinese medicine in prevention and treatment of renal tubular interstitial damage has achieved gratifying results, this article on the recent single-flavor extract the active ingredients of Chinese medicine and its prevention and treatment of glomerular diseases, tubular interstitial damage in experimental research to do a review. A blood circulation Huayu class 1.1 TMP TMP has the expansion of blood vessels, anti-platelet aggregation, improve blood rheology, anti-lipid oxidation and removal of the role of oxygen free radicals, etc. [2]. Ya-Ping Wang et al [3] using unilateral ureteral obstruction (UUO) model, observe the TMP on the extent of renal interstitial lesions and α-smooth muscle actin (αSMA) expression in renal interstitial situation. Results: The treatment group was the degree of renal interstitial damage significantly lighter than the control group (P lt;0.01); αSMA positive cells are also significantly lower than the control group (P lt;0.01). That muscle fibroblast (MyoF) involved in renal interstitial fibrosis in UUO model