Effect of Omega-3 Fatty Acids on Erythrocyte Membrane in Diabetic Rats.docVIP

下载本文档

1
0
约2.3万字
约 6页
2017-05-08 发布于上海
举报
版权申诉

Effect of Omega-3 Fatty Acids on Erythrocyte Membrane in Diabetic Rats.doc

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Effect of Omega-3 Fatty Acids on Erythrocyte Membrane in Diabetic Rats

Basic Science Macedonian Journal of Medical Sciences. 2011 Sep 30; 4(3):234-239. /10.3889/MJMS.1857-5773.2011.0180 Basic Science OPEN?ACCESS Effect of Omega-3 Fatty Acids on Erythrocyte Membrane in Diabetic Rats Jihan Hussein 1 *, Ehab Mostafa 2 , Maha El-Waseef 1 , Zakarya El-Khayat 1 , Ehsan Badawy 1 , Dalia Medhat 1 1 Medical Biochemistry Department, National Research Centre, Doki, Giza, 12311, Egypt; 2 Biochemistry Department ,Faculty of Science, Tanta University, Tanta, Egypt Abstract Citation: Hussein J, Mostafa E, El-Waseef M, El- Khayat Z, Badawy E, Medhat D. Effect of Omega- 3FattyAcidsonErythrocyteMembraneinDiabetic Rats. Maced J Med Sci. 2011 Sep 30; 4(3):234- Background: Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia resultingfromdefectsininsulinsecretion,almostalwayswithamajorcontributionfrominsulinresistance which may be affected by cell membrane fatty acids and phospholipids fractions. 239. 5773.2011.0180. /10.3889/MJMS.1957- Aim: To evaluate the effects of omega-3 fatty acids on erythrocyte membrane and also in decreasing oxidative stress in diabetic rats. Keywords:Omega-3;Fattyacids;Diabetes;Cell membrane; Phospholipids. Materials and Methods: Sixty healthy male albino rats weighting 180-200 g divided into five groups included: control, Omega-3, diabetic, prophylactic and treated groups. Fasting blood samples were collectedfromallgroupsfordeterminationoffastingbloodsugar,plasmainsulin, erythrocytemembrane lipid profile, phospholipids fractions by HPLC, plasma and erythrocyte membrane lipid peroxidation product (malondialdehyde) and reduced glutathione. Correspondence: Dr. Jihan S Hussein. Medical Biochemistry Center, Dokki, El-tahrer St.- Giza 12311, Egypt. E-Mail: jihan_husein@ Department, National Research Received: 26-Apr-2011; Revised: 29-May-2011; Accepted:28-Jun-2010;Onlinefirst:28-Aug-2011 Results: Fasting blood sugar and plasma insulin sensitivity were improved by Omega-3 administra