Antifungal activity of chemotype essential oils from rosemary against.docVIP

Open Journal of Stomatology, 2013, 3, 176-182 OJST /10.4236/ojst.2013.32031 Published Online May 2013 (/journal/ojst/) Antifungal activity of chemotype essential oils from rosemary against Candida albicans Yusuke Matsuzaki , Toshiyuki Tsujisawa , Tatsuji Nishihara , Mari Nakamura , 1 2 3 1 1* Yasuaki Kakinoki 1 Division of Oral Care and Rehabilitation, Department of Control of Physical Functions, Science of Physical Functions, Kyushu Dental University, Kitakyushu, Japan 2 Department of Oral Health Management, School of Oral Health Sciences, Kyushu Dental University, Kitakyushu, Japan Division of Infections and Molecular Biology, Department of Health Promotion, Science of Health Improvement, Kyushu Dental 3 University, Kitakyushu, Japan * Email: matsu.44.yum.44@ Received 13 March 2013; revised 26 April 2013; accepted 8 May 2013 Copyright ? 2013 Yusuke Matsuzaki et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT 1. INTRODUCTION Oral candidiasis is caused by Candida albicans. The symptoms including pain in the oral cavity affect our eating function. While some antifungal agents are commonly used for the treatment of candidiasis, oc- casional consumption of the effective dose cannot be tolerated due to side effects. There is also a possibility of induction of antifungal resistance, thus the devel- opment of replacement agents has been awaited. We aim to explore antimicrobial activities of essential oils. We evaluated the antifungal activities against C. al- bicans of essential oils from seven aromatic plants from three manufacturers, and of three chemotype essential oils from