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Chronic Wasting Disease—Prion Disease in the Wild
Feature
Chronic Wasting Disease—
Prion Disease in the Wild
Steve Bunk
I
n 1967, mule deer in a research
facility near Fort Collins,
Colorado, in the United States
epidemiologist at Colorado State
was ?rst diagnosed in deer east of
the Mississippi River, indicating a
potential nationwide problem. This
year, the USDA is developing a herd
certi?cation program to help prevent
the movement of infected animals in
the game farming industry. This will
bolster monitoring already underway
in virtually every state, including
postmortem examinations of game
killed by hunters and by sharpshooters
in mass culling operations.
University in Fort Collins. He’s been
scienti?cally involved with BSE, since it
was ?rst discovered among cattle in the
United Kingdom in 1986. He recalls
predicting that lay interest in BSE
would wane after ?ve years. Instead,
the disease was found in the mid-1990s
to be capable of killing humans who
ate tainted beef. “I was wrong, and it
really changed my way of thinking,
apparently began to react badly to
their captivity. At least, that was the
guess of researchers working on the
natural history and nutrition of the
deer, which became listless and showed
signs of depressed mood, hanging
their heads and lowering their ears.
They lost appetite and weight. Then
they died—of emaciation, pneumonia,
and other complications—or were
euthanized. The scientists dubbed
it chronic wasting disease (CWD),
and for years they thought it might
be caused by stress, nutritional
de?ciencies, or poisoning. A decade
later, CWD was identi?ed as one of
the neurodegenerative diseases called
spongiform encephalopathies, the most
notorious example of which is bovine
spongiform encephalopathy (BSE),
more commonly known as mad cow
disease. Nowadays, CWD is epidemic in
the United States. Although no proof
has yet emerged that it’s transmissible
to humans, scienti?c authorities
haven’t ruled out the possibility of
a public health threat. The media
have concentrated on this concern,
and
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