Compatibility in the Ustilago maydis–Maize Interaction Requires Inhibition of Host Cysteine Proteases by the Fungal Effector Pit2.docVIP

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Compatibility in the Ustilago maydis–Maize Interaction Requires Inhibition of Host Cysteine Proteases by the Fungal Effector Pit2.doc

Compatibility in the Ustilago maydis–Maize Interaction Requires Inhibition of Host Cysteine Proteases by the Fungal Effector Pit2

CompatibilityintheUstilagomaydis–MaizeInteraction RequiresInhibitionofHostCysteineProteasesbythe FungalEffectorPit2 Andre′ N.Mueller,SebastianZiemann,SteffiTreitschke¤,DanielaA?mann,GuntherDoehlemann* MaxPlanckInstituteforTerrestrialMicrobiology,Marburg,Germany Abstract The basidiomycete Ustilago maydis causes smut disease in maize, with large plant tumors being formed as the most prominentdiseasesymptoms.Duringallstepsofinfection,U.maydisdependsonabiotrophicinteraction,whichrequiresan efficient suppression of plant immunity. In a previous study, we identified the secreted effector protein P

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