原创力文档The yeast mitogen-activated protein kinase Slt2 is involved in the cellular response to genotoxic stress 英文论文文献.docVIP
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The yeast mitogen-activated protein kinase Slt2 is involved in the cellular response to genotoxic stress 英文论文文献
Soriano-Carotetal.CellDivision2012,7:1
/content/7/1/1
RESEARCH
OpenAccess
Theyeastmitogen-activatedproteinkinaseSlt2is
involvedinthecellularresponsetogenotoxic
stress
MaríaSoriano-Carot,MCarmen Ba?óandJCarlosIgual*
Abstract
Background:Themaintenanceofgenomicintegrityisessentialforcellviability.Complexsignallingpathways
(DNAintegritycheckpoints)mediatetheresponsetogenotoxicstresses.Identifyingnewfunctionsinvolvedinthe
cellularresponsetoDNA-damageiscrucial.TheSaccharomycescerevisiaeSLT2geneencodesamemberofthe
mitogen-activatedproteinkinase(MAPK)cascadewhosemainfunctionisthemaintenanceofthece
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