Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization 英文论文文献.docVIP
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Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization 英文论文文献
Luoetal.BMCSystemsBiology2011,5:82
/1752-0509/5/82
RESEARCH ARTICLE
OpenAccess
Timeseriesgeneexpressionprofilingandtemporal
regulatorypathwayanalysisofBMP6induced
osteoblastdifferentiationandmineralization
WeijunLuo1,2,MichaelSFriedman3,KurtDHankenson4* andPeterJWoolf1,5,6*
Abstract
Background:BMP6mediatedosteoblastdifferentiationplaysakeyroleinskeletaldevelopmentandbonedisease.
Unfortunately,thesignalingpathwaysregulatedbyBMP6arelargelyuncharacterizedduetobothalackofdata
andthecomplexityoftheresponse.
Results:TobettercharacterizethesignalingpathwaysresponsivetoBMP6,weconductedatimeserie
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