Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization 英文论文文献.docVIP

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Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization 英文论文文献.doc

Time series gene expression profiling and temporal regulatory pathway analysis of BMP6 induced osteoblast differentiation and mineralization 英文论文文献

Luoetal.BMCSystemsBiology2011,5:82 /1752-0509/5/82 RESEARCH ARTICLE OpenAccess Timeseriesgeneexpressionprofilingandtemporal regulatorypathwayanalysisofBMP6induced osteoblastdifferentiationandmineralization WeijunLuo1,2,MichaelSFriedman3,KurtDHankenson4* andPeterJWoolf1,5,6* Abstract Background:BMP6mediatedosteoblastdifferentiationplaysakeyroleinskeletaldevelopmentandbonedisease. Unfortunately,thesignalingpathwaysregulatedbyBMP6arelargelyuncharacterizedduetobothalackofdata andthecomplexityoftheresponse. Results:TobettercharacterizethesignalingpathwaysresponsivetoBMP6,weconductedatimeserie

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