Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis 英文论文文献.docVIP

Rivera et al. BMC Gastroenterology 2010, 10:52 /1471-230X/10/52 RESEARCH ARTICLE Open Access Toll-like receptor-2 deficiency enhances Research article non-alcoholic steatohepatitis Chantal A Rivera*1,2, LaTausha Gaskin1, Monique Allman1, Jia Pang1, Kristen Brady1, Patrick Adegboyega1 and Kevin Pruitt1 Abstract Background: Previously we reported that mice deficient in toll-like receptor 4 (TLR-4) signalling were protected from diet-induced non-alcoholic steatohepatitis (NASH). Another member of the toll-like receptor family, TLR-2, has been shown to play a role in lipid trafficking via