Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data 英文论文文献.docVIP

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Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data 英文论文文献.doc

Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data 英文论文文献

Lietal.BMCBioinformatics2012,13:109 /1471-2105/13/109 METHODOLOGY ARTICLE OpenAccess Towardstheidenti?cationofprotein complexesandfunctionalmodulesby integratingPPInetworkandgeneexpression data MinLi1,2*,XuehongWu1,JianxinWang1*andYiPan1,3* Abstract Background: Identi?cationofproteincomplexesandfunctionalmodulesfromprotein-proteininteraction(PPI) networksiscrucialtounderstandingtheprinciplesofcellularorganizationandpredictingproteinfunctions.Inthe pastfewyears,manycomputationalmethodshavebeenproposed.However,mostofthemconsideredthePPI networksasstaticgraphsandoverlookedthedynamicsinherentwi

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Towards the identification of protein complexes and functional modules by integrating PPI network and gene expression data 英文论文文献.docVIP