Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII 英文论文文献.docVIP

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Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII 英文论文文献.doc

Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII 英文论文文献

Swiechetal.BMCBiotechnology2011,11:114 /1472-6750/11/114 RESEARCH ARTICLE OpenAccess Transienttransfectionofserum-freesuspension HEK293cellcultureforefficientproductionof humanrFVIII KamillaSwiech1,2*,AmineKamen3,SvenAnsorge3,YvesDurocher3,VirgíniaPican?o-Castro1, ElisaMSRusso-Carbolante1,4,MárioSANeto1andDimasTCovas1,5 Abstract Background:HemophiliaAisableedingdisordercausedbydeficiencyincoagulationfactorVIII.Recombinant factorVIII(rFVIII)isanalternativetoplasma-derivedFVIIIforthetreatmentofhemophiliaA.However,commercial manufacturingofrFVIIIproductsisinefficientandcostlyandisassociatedtoh

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Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII 英文论文文献.docVIP