TTFields alone and in combination with chemotherapeutic agents effectively reduce the viability of MDR cell sub-lines that over-express ABC transporters 英文论文文献.docVIP

Schneiderman et al. BMC Cancer 2010, 10:229 /1471-2407/10/229 RESEARCH ARTICLE Open Access TTFields alone and in combination with Research article chemotherapeutic agents effectively reduce the viability of MDR cell sub-lines that over-express ABC transporters Rosa S Schneiderman?1, Esther Shmueli1, Eilon D Kirson1 and Yoram Palti*?1,2 Abstract Background: Exposure of cancer cells to chemotherapeutic agents may result in reduced sensitivity to structurally unrelated agents, a phenomenon known as multidrug resistance, MDR. The purpose of this study is to investigate cell growth inhibi