Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity 英文论文文献.docVIP

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Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity 英文论文文献.doc

Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity 英文论文文献

Cerkovniketal.BMCImmunology2010,11:45 /1471-2172/11/45 RESEARCH ARTICLE OpenAccess TumorvaccinecomposedofC-classCpG oligodeoxynucleotidesandirradiatedtumorcells induceslong-termantitumorimmunity PetraCerkovnik1,BarbaraJezersekNovakovic2,VidaStegel1,SrdjanNovakovic1* Abstract Background:Anidealtumorvaccineshouldactivatebotheffectorandmemoryimmuneresponseagainsttumor- specificantigens.BesidetheCD8+Tcellsthatplayacentralroleinthegenerationofaprotectiveimmune responseandoflong-termmemory,dendriticcells(DCs)areimportantfortheinduction,coordinationand regulationoftheadaptiveimmuneresponse.TheDCsc

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Tumor vaccine composed of C-class CpG oligodeoxynucleotides and irradiated tumor cells induces long-term antitumor immunity 英文论文文献.docVIP