Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes 英文论文文献.docVIP

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Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes 英文论文文献.doc

Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes 英文论文文献

Buschetal.BMCGenomics2010,11:65 /1471-2164/11/65 RESEARCH ARTICLE OpenAccess Tungstencarbidecobaltnanoparticlesexert hypoxia-likeeffectsonthegeneexpressionlevel inhumankeratinocytes WibkeBusch1*,DanaKühnel1,KristinSchirmer2,StefanScholz1 Abstract Background:Tungstencarbide(WC)andtungstencarbidecobalt(WC-Co)nanoparticlesareofoccupationalhealth relevancebecauseoftheincreasingusageinhardmetalindustries.Earlierstudiesshowedanenhancedtoxic potentialforWC-CocomparedtoWCorcobaltionsalone.Therefore,weinvestigatedtheimpactoftheseparticles, comparedtocobaltionsappliedasCoCl2,ontheglobalgeneexpression

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