原创力文档TWIST1, A novel androgen-regulated gene, is a target for NKX3-1 in prostate cancer cells 英文论文文献.docVIP
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TWIST1, A novel androgen-regulated gene, is a target for NKX3-1 in prostate cancer cells 英文论文文献
Eideetal.CancerCellInternational2013,13:4
/content/13/1/4
PRIMARY RESEARCH
OpenAccess
TWIST1,Anovelandrogen-regulatedgene,isa
targetforNKX3-1inprostatecancercells
TuridEide1*,H?konRamberg1,CarlottaGlackin3,DonaldTindall4andKristinAustlidTaskén1,2
Abstract
Background:TWIST1playsakeyroleinEMT-mediatedtumorinvasionandmetastasis.Sincebonemetastasisisa
hallmarkofadvancedprostatecancerandisdetectedinatleast85%ofpatientswhodieofthisdisease,itisof
greatimportancetounderstandtheregulationofthecellularsignalingpathwaysinvolvedinthemetastaticprocess.
Methods:Prostaticcelllineswereanalyzedusingrealtime
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