Using epitope predictions to evaluate efficacy and population coverage of the Mtb72f vaccine for tuberculosis 英文论文文献.docVIP

McNamara et al. BMC Immunology 2010, 11:18 /1471-2172/11/18 RESEARCH ARTICLE Open Access Using epitope predictions to evaluate efficacy and Research article population coverage of the Mtb72f vaccine for tuberculosis Lucy A McNamara1,2, Yongqun He2,3,4 and Zhenhua Yang*1 Abstract Background: The Mtb72f subunit vaccine for tuberculosis, currently in clinical trials, is hoped to provide improved protection compared to the current BCG vaccine. It is not clear, however, whether Mtb72f would be equally protective in the different human populations suffering from a high burden of tuberculosi