Using machine learning to speed up manual image annotation application to a 3D imaging protocol for measuring single cell gene expression in the developing C. elegans embryo 英文论文文献.docVIP
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Using machine learning to speed up manual image annotation application to a 3D imaging protocol for measuring single cell gene expression in the developing C. elegans embryo 英文论文文献
Aydinetal.BMCBioinformatics2010,11:84
/1471-2105/11/84
RESEARCH ARTICLE
OpenAccess
Usingmachinelearningtospeedupmanual
imageannotation:applicationtoa3Dimaging
protocolformeasuringsinglecellgene
expressioninthedevelopingC.elegansembryo
ZaferAydin1*,JohnIMurray1,RobertHWaterston1,WilliamSNoble1,2
Abstract
Background:Imageanalysisisanessentialcomponentinmanybiologicalexperimentsthatstudygene
expression,cellcycleprogression,andproteinlocalization.AprotocolfortrackingtheexpressionofindividualC.
elegansgeneswasdevelopedthatcollectsimagesamplesofadevelopingembryoby3-Dtimelapsemicroscopy.
Inthispro
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