原创力文档Using Stochastic Causal Trees to Augment Bayesian Networks for Modeling eQTL Datasets 英文论文文献.docVIP
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Using Stochastic Causal Trees to Augment Bayesian Networks for Modeling eQTL Datasets 英文论文文献
ChipmanandSinghBMCBioinformatics2011,12:7
/1471-2105/12/7
RESEARCH ARTICLE
OpenAccess
UsingStochasticCausalTreestoAugment
BayesianNetworksforModelingeQTLDatasets
KyleCChipman1*,AmbujKSingh1,2
Abstract
Background:Thecombinationofgenotypicandgenome-wideexpressiondataarisingfromsegregating
populationsoffersanunprecedentedopportunitytomodelanddissectcomplexphenotypes.Theimmense
potentialofferedbythesedataderivesfromthefactthatgenotypicvariationisthesolesourceofperturbationand
canthereforebeusedtoreconcilechangesingeneexpressionprogramswiththeparentalgenotypes.Todate,
severalmethodologieshavebee
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