Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice 英文论文文献.docVIP
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Vaccination with human anti-trastuzumab anti-idiotype scFv reverses HER2 immunological tolerance and induces tumor immunity in MMTV.f.huHER2(Fo5) mice 英文论文文献
Ladjemietal.BreastCancerResearch2011,13:R17
/content/13/1/R17
RESEARCH ARTICLE
OpenAccess
Vaccinationwithhumananti-trastuzumab
anti-idiotypescFvreversesHER2immunological
toleranceandinducestumorimmunityin
MMTV.f.huHER2(Fo5)mice
MahaZLadjemi1,ThierryChardes1,StephanieCorgnac1,VeroniqueGarambois1,SebastienMorisseau1,
BrunoRobert1,CarolineBascoul-Mollevi2,ImadeAitArsa1,WilliamJacot2,Jean-PierrePouget1,AndrePelegrin1,
IsabelleNavarro-Teulon1*
Abstract
Introduction:NoveladjuvanttherapiesareneededtopreventmetastaticrelapsesinHER2-expressingbreast
cancer.Here,wetestedwhethertrastuzumab-selectedsingl
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