Validated spectrophotometric methods for determination of Alendronate sodium in tablets through nucleophilic aromatic substitution reactions 英文论文文献.docVIP

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Validated spectrophotometric methods for determination of Alendronate sodium in tablets through nucleophilic aromatic substitution reactions 英文论文文献.doc

Validated spectrophotometric methods for determination of Alendronate sodium in tablets through nucleophilic aromatic substitution reactions 英文论文文献

Walashetal.ChemistryCentralJournal2012,6:25 /content/6/1/25 RESEARCH ARTICLE OpenAccess Validatedspectrophotometricmethodsfor determinationofAlendronatesodiumintablets throughnucleophilicaromaticsubstitution reactions MohamedIWalash,MohamedE-SMetwally,ManalEidandRaniaNEl-Shaheny* Abstract Background:Alendronate(ALD)isamemberofthebisphosphonatefamilywhichisusedforthetreatmentof osteoporosis,bonemetastasis,Paget’sdisease,hypocalcaemiaassociatedwithmalignancyandotherconditions thatfeaturebonefragility.ALDisanon-chromophoriccompoundsoitsdeterminationbyconventional spectrophotometricmethodsisnot

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Validated spectrophotometric methods for determination of Alendronate sodium in tablets through nucleophilic aromatic substitution reactions 英文论文文献.docVIP