原创力文档Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer 英文论文文献.docVIP
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Validation of podocalyxin-like protein as a biomarker of poor prognosis in colorectal cancer 英文论文文献
Larssonetal.BMCCancer2012,12:282
/1471-2407/12/282
RESEARCH ARTICLE
OpenAccess
Validationofpodocalyxin-likeproteinasa
biomarkerofpoorprognosisincolorectalcancer
AnnaLarsson1*,MarieFridberg1,AlexanderGaber1,Bj?rnNodin1,PerLevéen1,G?ranJ?nsson2,MathiasUhlén3,
HelgiBirgisson4andKarinJirstr?m1
Abstract
Background:Podocalyxin-like1(PODXL)isacell-adhesionglycoproteinandstemcellmarkerthathasbeen
associatedwithanaggressivetumourphenotypeandadverseoutcomeinseveralcancertypes.Werecently
demonstratedthatoverexpressionofPODXLisanindependentfactorofpoorprognosisincolorectalcancer(CRC).
Theaimofthisstudy
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