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Very ‘sticky’ proteins – not too sticky after all 英文论文文献
FellerandLewitzkyCellCommunicationandSignaling2012,10:15
/content/10/1/15
COMMENTARY
OpenAccess
Very‘sticky’proteins–nottoostickyafterall?
StephanMFeller*andMarcLewitzky
Abstract
Aconsiderablenumberofsolubleproteinsincellsthatbiochemiststrytoanalyzearedifficulttohandlebecause
theyseemtobehavelikespongesthat‘suckup’manyotherproteins.Weargueherethatthisbehavioris
commonlyanartifactintroducedbytheexperimentingscientistandthatweneedtostudyproteinslikeanimalsin
thewild:theywillonlyrevealmanyoftheirsecretswhencarefullyobservedintheirlargelyundisturbed,natural
environment.Computationalstudiesthatat
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