三种不同类型抗菌药物治疗老年社区获得性肺炎的成本-效果分析.pdfVIP

2012 年 2 月第 50 卷第4 期 ·临床研究· 三种不同类型抗菌药物治疗老年社区获得性肺炎的 成本-效果分析 赵永龙 温州医学院附属第一医院文成院区呼吸科，浙江文成 325300 [摘要]目的探讨三种不同类型抗菌药物治疗老年社区获得性肺炎的成本与临床效果关系。.方法将 90 例老年社 区获得性肺炎患者随机分为 A 组(30 例)、B 组(30 例)及 C 组(30 例) ，分别给予左氧氟沙星注射液、阿奇霉素注射 液、头抱赈嗣-舒巴坦铀注射液每日静脉滴注，三组总疗程均为 10 d ，运用药物经济学原理进行成本-效果分析。结 果 3 种药物治疗老年社区获得性肺炎的有效率分别为 83.39毛、76.7% 、 86.7%(P 0.05) ，细菌清除率分别为 88iJ岛、 79.29毛、92.3% (P 0.05) ，且药物不良反应少，三组间比较差异无统计学意义;成本-效果比分别为(有效率) 9.9 、 14.7 、 20札(细菌清除率)分别为 9.3 ， 14.2 、 18.7 ， A 组成本-效果比最小。结论左氧氟沙星注射液治疗老年社区获得 性肺炎效果显著，安全可靠，值得基层医院临床推广应用。 [关键词]社区获得性肺炎;左氧氟沙皇;阿奇霉素;头抱吁在嗣一舒巳坦纳;成本效果分析 [申图分类号] R563.1 [文献标识码] B [文章编号] 1673-9701(2012)04-0067-03 Cost-efTectiveness analysis of three difTerent types of antibiotics in treatment of elderly patients with community acquired pneumonia ZHA 0 Yonglong Department of Respiratory , Wencheng Division of the First Affiliated Hospital of Wenzhou Medical College ,Wencheng 325300, China [Abstract] Objective To investigate the relationship between cost and clinical effectiveness of three different types of antibiotic in treatment of elderly patients with community acquired pneumonia. Methods All of 90 elderly patients with community acquired pneumonia were randomly divided into group A (30 cases) , B group (30 cases) and Group C (30 cases) , which were respectively treated with levofloxacin , azithromycin and cefoperazone - sulbactam for 10d ,then used the pharmacoeconomic principles for cost-effectiveness analysis. Results For group A ,B and C ,effectiveness respectively were 83 .3%, 76.7% , 86.7% (P0.05) ,bacterial clearance rates were 889毛 ， 79.2% , 92.3%(P 0.05) ,and the incidence of adverse drug reactions were low ,the