经导引导管持续注入尼莫地平治疗颅内动脉瘤栓塞术并发脑血管痉挛的疗效.pdfVIP

1072 Guang冗i Medical lournal. ,Au/{. .2016 , Vol. 38 ,No. 8 经导引导管持续注入尼莫地平治疗 颅内动脉瘤栓塞术并发脑血管痊擎的疗效A 陆弘盈谭适草重桥余松种张文佳周铭臻 (广西医科大学第八附属医院暨贵港市人民医院神经外一科，贵港市 537100 ,E-mail:219219219@) [摘要] 目的 探讨经导引导管持续注入尼莫地平治疗颅内动脉瘤栓塞术并发脑血管痊孪(CVS) 的疗效。方法 行 颅内动脉瘤栓塞术并发 CVS 的蛛网膜下腔出血患者 60 例，随机分为对照纽和观察组，每组 30 例。两组均给予扩充血容 量、升高血压、稀释血液等常规治疗，对照纽给予尼莫地平静脉滴注，观察纽给予经导引导管颅内注入尼莫地平治疗，7 d 后 改口服，疗程7 d。比较两组解痊所需时间、治疗前后血压、11各床疗效及格拉斯哥预后量表(GOS) 分级。结果 观察纽解痊 所需时间短于对照纽(P 0. 05) 。治疗后，对照组血压显著降低，并且低于观察组(P 0.05) ，观察组治疗前后血压比较， 差异无统计学意义(P 0. 05) 。观察组疗效及 GOS 分级优于对照纽(P 0.05) 。结论 经导引导管持续注入尼莫地平治 疗颅内动脉瘤栓塞术并发 CVS 效采好，可缩短解痊时间。 {关键词] 蛛网膜下腔出血;脑血管痊孪;颅内动脉瘤栓塞术;尼莫地平;导管注入;并发症 [中图分类号1 R 743 [文献标识码1 A [文章编号1 0253-4304(2016)08-1072-03 DOI; 10. 11675/j. issn. 0253-4304. 2016. 08. 06 Efficacy of continuous trans-伊iding catheter infusion with nimodipine for treatment of cerebral vascular spasm caused by intracranial aneurysm embolization LU Hong-ying , TAN Shi , QIN Chong-仰， YU Song-zuo ,ZHANG Wen忡， ZHOU Ming-tai ( The First Department of Neuros叫百町， the Eighth Affil皿ted Hospital of Guangxi Medical University , Guigang People s Hospi时， Guigang 5371∞， China) [ Abstract 1 Objective To explore the efficacy of continuous trans-guiding catheter infusion with nimodipine for the treatment of cerebral vascular spasm ( CVS) caused by intracranial aneuηsm embolization. Methods Sixty patients with subarachnoid hemorrhage suffered from CVS caused by intracranial aneurysm embolization and were randomly divided into control group ( n = 30) and observation group (n = 30) _ The routine therapy including volume resuscitation , blood pressure elevation and hemodilution was performed in both groups. The control group was