Basal Cell Carcinoma of the Head and Neck Region in Ethnic Chinese英文文献资料.docVIP

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Basal Cell Carcinoma of the Head and Neck Region in Ethnic Chinese英文文献资料.doc

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Basal Cell Carcinoma of the Head and Neck Region in Ethnic Chinese英文文献资料

HindawiPublishingCorporation InternationalJournalofSurgicalOncology Volume2011,ArticleID890908,7pages doi:10.1155/2011/890908 ClinicalStudy BasalCellCarcinomaoftheHeadandNeck RegioninEthnicChinese VeldaLingYuChow,JimmyYuWaiChan,RichieChiuLungChan, JosephHonPingChung,andWilliamIgnaceWei DivisionofHeadandNeck,PlasticandReconstructiveSurgery,DepartmentofSurgery,QueenMaryHospital, TheUniversityofHongKong,PokfulamRoad,HongKong CorrespondenceshouldbeaddressedtoVeldaLingYuChow,vlychow@ Received1May2011;Revised4June2011;Accepted8June2011 AcademicEditor:MichaelVeness Copyright?2011VeldaLingYuChowetal.ThisisanopenaccessarticledistributedundertheCreativeCommonsAttribution License,whichpermitsunrestricteduse,distribution,andreproductioninanymedium,providedtheoriginalworkisproperly cited. Objectives.ThisstudyaimstoreportourexperienceinthemanagementofHNBCCinethnicChineseovera10-yearperiod. Methods.AretrospectivereviewofallethnicChinesepatientswithHNBCCtreatedinatertiarycentrefrom1999to2009.Results. From1999to2009,225patientsunderwentsurgicalexcisionforHNBCC.Majoritywereelderlyfemalepatients.Commonest presentationwasapigmented(76.2%)ulcer(64.8%)overthenose(31.6%).Medianskinmargintakenontumourexcisionwas 2.0mm;primaryskinclosurewasachievedin51.8%.Postresectionskinmarginwasclearin75.4%.Ofthosewithinadequate skinmargins,56.7%optedforfurthertreatment,43.4%forobservation.Recurrencerateswere2.6%and13.8%,respectively (P =0.106).Overallrecurrenceratewas5.5%.Conclusions.HNBCCcommonlypresentedaspigmentedulcersoverthenoseof elderlyfemalepatientsinourlocality.Adequatetumourexcision± reconstructiono?eredthebestchanceofcure.Reexcisionof thosewithinadequateskinmarginsimprovedlocaltumourcontrol. 1.Introduction electrodessication,cryosurgeryhavebeenreportedwithvari- abletreatmentoutcomes;similarly,topicalandintralesional agents, photodynamic therapy have also been described, again with variable outcomes, warranting careful patient selection[11–14]. MuchhasbeenpublishedregardingBCCsinCaucasia