Proteintraffickingbetweenmembranes-Chapter4.pptVIP

Chapter 4 Protein trafficking between membranes By Graham Warren Ira Mellman 4.1 Introduction Eukaryotic cells have an elaborate system of internal membrane-bounded structures called organelles. Each organelle: has a unique composition of (glyco)proteins and (glyco)lipids carries out a particular set of functions An organelle comprises one or more membrane-bounded compartments. Organelles may act autonomously or in cooperation to accomplish a given function. In the endocytic and exocytic pathways, cargo proteins are transferred between compartments by transport vesicles. The vesicles form