Breaking the News or Fueling the Epidemic Temporal Association between News Media Report Volume and Opioid-Related Mortality 英文参考文献.docVIP

BreakingtheNewsorFuelingtheEpidemic?Temporal AssociationbetweenNewsMediaReportVolumeand Opioid-RelatedMortality NabarunDasgupta1,KennethD.Mandl2,3,4,JohnS.Brownstein2,3,4 * 1DepartmentofEpidemiology,GillingsSchoolofGlobalPublicHealth,UniversityofNorthCarolina,ChapelHill,NorthCarolina,UnitesStatesofAmerica,2Children’s HospitalInformatics ProgramatHarvard–MassachusettsInstitute ofTechnology, DivisionofHealthSciences andTechnology, Boston, Massachusetts, UnitedStates of America,3DivisionofEmergencyMedicine,Children’sHospitalBoston,Boston, Massachusetts,UnitedStatesofAmerica, 4Department ofPediatrics,HarvardMedical School,Boston,Massachusetts,UnitedStatesofAmerica Abstract Background:Historicalstudiesofnewsmediahavesuggestedanassociationbetweenreportingandincreaseddrugabuse. Period effects for substance use have been documented for different classes of legal and illicit substances, with the suspicion that media publicity may have played major roles in their emergence. Previous analyses have drawn primarily fromqualitativeevidence;thetemporalrelationshipbetweenmediareportingvolumeandadversehealthconsequences hasnotbeenquantifiednationally.Wesetouttoexplorewhetherwecouldfindaquantitativerelationshipbetweenmedia reports about prescription opioid abuse and overdose mortality associated with these drugs. We assessed whether increasesinnewsmediareportsoccurredbeforeorafterincreasesinoverdosedeaths. Methodology/PrincipalFindings:Ourecologicalstudycomparedamonthlytimeseriesofunintentionalpoisoningdeaths involvingshort-actingprescriptionopioidsubstances,from1999to2005usingmultiplecause-of-deathdatapublishedby the National Center for Health Statistics, to monthly counts of English-language news articles mentioning generic and branded names of prescription opioids obtained from Google News Archives from 1999 to 2005. We estimated the associationbetweenmediavolumeandmortalityratesbytime-laggedregressionanalyses.Therewere24,272articlesand 30,916 deaths involving prescript