Diagnosis, Clinical Features, and Self-Reported Morbidity of Strongyloides stercoralis and Hookworm Infection in a Co-Endemic Setting 英文参考文献.docVIP

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Diagnosis, Clinical Features, and Self-Reported Morbidity of Strongyloides stercoralis and Hookworm Infection in a Co-Endemic Setting 英文参考文献.doc

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Diagnosis, Clinical Features, and Self-Reported Morbidity of Strongyloides stercoralis and Hookworm Infection in a Co-Endemic Setting 英文参考文献

Diagnosis,ClinicalFeatures,andSelf-ReportedMorbidity ofStrongyloidesstercoralisandHookwormInfectionina Co-EndemicSetting So¨renL.Becker1,2,3,BenjaminSieto4,KigbaforiD.Silue′5,6,LucasAdjossan7,SiakaKone′6 ,Christoph Hatz2,8,9,WinfriedV.Kern3,Elie′zerK.N’Goran5,6,Ju¨rgUtzinger1,2 * 1Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland, 2University of Basel, Basel, Switzerland, 3Center for InfectiousDiseasesandTravelMedicine,DepartmentofMedicine,UniversityHospitalFreiburg,FreiburgimBreisgau,Germany,4DispensaireRuraldeLe′le′ble′,Le′le′ble′, Co?te d’Ivoire, 5Laboratoire de Zoologie et Biologie Animale, Unite′ de Formation et de Recherche (UFR) Biosciences, Universite′ de Cocody, Abidjan, Co?te d’Ivoire, 6De′partementEnvironnementetSante′, CentreSuissedeRecherchesScientifiquesenCo?ted’Ivoire,Abidjan,Co?ted’Ivoire,7Ho?pitalGeneraldeTaabo-Cite′,Taabo-Cite′, Co?te d’Ivoire, 8Department of Medical Services and Diagnostic, Swiss Tropical and Public Health Institute, Basel, Switzerland, 9Institute for Social and Preventive Medicine,UniversityofZurich,Zurich,Switzerland Abstract Background:InfectionswithStrongyloidesstercoralisandotherhelminthsrepresentimportant,yetoftenneglectedissuesin developingcountries.Indeed,strongyloidiasiscanbefatal,butonlyafewstudiesprovideinformationregardingitshealth relevance in Africa. Moreover, clinical data on symptomatology and typical recognition patterns mainly originate from Westerntravelclinics. Methodology:Across-sectionalepidemiologicalsurveywascarriedoutinaruralpartofsouth-centralCo?ted’Ivoire.Stool samples from 292 randomly selected individuals were examined for intestinal helminths, using a suite of diagnostic techniques (i.e., Kato-Katz, Baermann funnel, and Koga agar plate). Participants were interviewed with a pre-tested questionnaireandclinicallyexamined.Multivariatelogisticregressionanalysiswasdonetorelateperceivedmorbidityand clinicalfindingstohelminthinfectionstatus. Prin