Free Antiretrovirals Must Not Be Restricted Only to Treatment-Naive Patients 英文参考文献.docVIP

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Free Antiretrovirals Must Not Be Restricted Only to Treatment-Naive Patients 英文参考文献.doc

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Free Antiretrovirals Must Not Be Restricted Only to Treatment-Naive Patients 英文参考文献

Open access, freely available online Essay Free Antiretrovirals Must Not Be Restricted Only to Treatment-Naive Patients Experience in Uganda suggests that restricting access is not the way forward Robert Colebunders, Moses Kamya, Fred Semitala, Barbara Castelnuovo, Elly Katabira, Keith McAdam* D espite the “3 by 5” initiative [1], which aims to treat 3 million people with antiretrovirals (ARVs) by the end of 2005, access to ARVs in resource-poor settings remains limited. Moreover, in some ARV-access programmes, free ARVs are provided only, or preferentially, to patients who are ARV naive. Why Programmes Restrict Access There are four principal reasons why free ARVs are being restricted to treatment-naive patients. Firstly, ARV treatment Treatment restricted to patients who are ARV naive was initially the case in Uganda, with the free ARVs provided by the Multi-Country AIDS Programme and the Presidential Emergency Plan for AIDS Relief. While in the policy documents of both projects it was not stated that free ARVs should be given preferentially to ARV-naive patients, many physicians involved in the roll-out of ARVs in Uganda felt that this was what these projects were recommending. Indeed, the Ministry of Health’s “Antiretroviral Treatment Policy for Uganda” stated that “those who are clinically eligible and can afford to pay for ART will be encouraged to do so. Those already in privately provided and privately paid ART should be encouraged to remain in this situation. Others who become clinically eligible over time and have the ability to pay or have a third party able to pay in their place or cost share with them, should pay full cost for ART, whether they avail themselves of treatment provided in the public or private sector” [2]. These policy statements were interpreted by many clinicians to mean that patients who are already paying for their drugs can afford to do so and are not a priority for free drugs. regimens are more predictable in ARV- naive patient