Large-Scale Clonal Analysis Reveals Unexpected Complexity in Surface Ectoderm Morphogenesis 英文参考文献.docVIP

Large-ScaleClonalAnalysisRevealsUnexpected ComplexityinSurfaceEctodermMorphogenesis Anne-Ce′cilePetit,Jean-Franc?ois Nicolas* Unite′ deBiologiemole′culaireduDe′veloppement,InstitutPasteur,Paris,France Abstract Background: Understanding the series of morphogenetic processes that underlie the making of embryo structures is a highlytopicalissueindevelopmentalbiology,essentialforinterpretingthemassivemoleculardatacurrentlyavailable.In mouseembryo,long-terminvivoanalysisofcellbehavioursandmovementsisdifficultbecauseofthedevelopmentinutero andtheimpossibilityoflong-termculture. Methodology/Princi