原创力文档Large-Scale Assessment of the Zebrafish Embryo as a Possible Predictive Model in Toxicity Testing 英文参考文献.docVIP
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Large-Scale Assessment of the Zebrafish Embryo as a Possible Predictive Model in Toxicity Testing 英文参考文献
Large-ScaleAssessmentoftheZebrafishEmbryoasa
PossiblePredictiveModelinToxicityTesting
ShaukatAli1,HaraldG.J.vanMil1,2,MichaelK.Richardson1*
1InstituteofBiology,SylviusLaboratory,LeidenUniversity,Leiden,TheNetherlands,2MathematicalInstitute,LeidenUniversity,Leiden,TheNetherlands
Abstract
Background:Inthedrugdiscoverypipeline,safetypharmacologyisamajorissue.Thezebrafishhasbeenproposedasa
modelthatcanbridgethegapinthisfieldbetweencellassays(whicharecost-effective,butlowindatacontent)androdent
assays(whicharehighindatacontent,butlesscost-efficient).However,zebrafishassaysareonlylikelytobeusefulift
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